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RSO GUIDELINES FOR IODINATIONS The
following guidelines and requirements are put forth to aid the
investigator in establishing safe iodination procedures and complying with
existing RSO policies. REQUIREMENTS: Prior
RSO Approval of Protocol A
written protocol and a summary of each individual’s experience must be
submitted to and approved by the RSO.
Forms RSO-BIO1 and BIO2 must be used. Fume
hood checkout The
RSO must perform an air flow check of the hood to be used in order to
verify adequate air flow. A
label will be applied to the front side of the hood sash indicating that a
check was performed. Survey
Instrument A
survey instrument equipped with a NaI detector must be present during the
procedure. This instrument
must be in calibration. Personnel
monitoring Dosimetry--Personnel dosimetry must be worn by the participating individuals if the stock vial of Iodine to be used contains ³ 5 mCi. Bioassay--Baseline
thyroid probes are required for individuals performing an iodination for
the first time.
Subsequently, thyroid probes are required within 48 hours after
each iodination. The Radiation Safety Office may grant exceptions to this
requirement on a case-by-case basis Air
monitoring In order to allow monitoring of the radioactive effluent during the iodination procedure, an air sampling probe must be installed in the exhaust duct of the fume hood. The probe will be provided by the Radiation Safety Office, but the installation will need to be performed by your institution's maintenance department. Notification Contact
the Radiation Safety Office 24 hours in advance of each iodination.
This will allow adequate time to set up air sampling pumps and
schedule bioassays. PROCEDURAL
GUIDELINES: A.
The iodinator is responsible for starting and stopping the air
sampling pumps and recording the start/stop times on a standardized form.
Other information to be noted on this form includes the total
activity used, the names of the Authorized User and involved individuals,
the date of iodination, and the package ID#. B.
Set up a defined work area including waste repository and survey
instrument station. All work
surfaces must be covered with absorbent padding. C.
Take standard lab precautions such as wearing protective clothing
and gloves (double gloves are recommended if
they do not inhibit the experimenter).
All non-participating lab personnel should be out of the lab during
the procedure. D.
At the conclusion of the procedure, consolidate all waste materials
into approved yellow bags and either take to the radioactive waste room or
place in the hood. Utilizing the survey instrument, perform monitoring of the experiment area and all personnel involved. Performa a contamination survey of the area and document the results on a standard lab survey form. For multiple user laboratories, post the hood with a sign indicating that the hood should not be used until it has been surveyed for contamination. E. Schedule a thyroid probe through UPMC Radiation Medicine, at 647-3595
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Radiation Safety Office Webmaster Revised September 27, 2001 |
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